Burn Wound Healing Activity of Euphorbia Hirta

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Ancient Science of Life

Vol : XXV (3 & 4) January, February, March & April, May, June 2006

BURN WOUND HEALING ACTIVITY OF Euphorbia hirta
Jaiprakash.B1, Chandramohan2, D.Narasimha Reddy1 CMR College of Pharmacy, C.A.No.5, Bhuvanagiri, OMBR Layout, Bangalore-560 043. 2 Bharathi College of Pharmacy, Bharathi Nagar, Mandya (Dt), Karnataka Received : 19-10-2005 Accepted : 12-12-2005 ABSTRACT The Ethanolic extract of whole plant of Euphorbia hirta was screened for burn wound healing activity in rats as 2% W/W cream. The study was carried out based on the assessment of percentage reduction in original wound. It showed significant burn wound healing activity. INTRODUCTION: Tissue damage from excessive heat, electricity, radioactivity or corrosive chemicals that destroy (denature) protein in the exposed cells is called a burn. Burns disrupt haemostasis because they destroy the protection afforded by the skin. They permit microbial invasion and infection, loss of body fluid and loss of thermoregulation.1 Several indigenous drugs have been described in Ayurveda (an ancient Indian system of Medicine) for the management of wounds and burns. Hence, in an attempt to study the wound healing activity of several locally available indigenous herbs, we studied and reported the wound healing activity of the ethonalic extract of the whole plant of Euphorbia hirta in various models like excision, incision and dead space wounds.2 In this communication we report the bourn wound healing activity of the same. Euphorbia hirta Linn. Syn. Euphorbia pilulifera auct. non Linn., (Euphorbiaceae) is an annual, erect or
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ascending herb with hairy stems which is distributed throughout the warmer regions of India.3, 4 The decoction and juice of the plant is used as antiasthmatic and have been found very beneficial in case of asthma. It is used as astringent in chronic diarrhea and dysentery. It is…...

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