Nick

In: Business and Management

Submitted By ruiznik
Words 640
Pages 3
Case Study

1. Review the four principles of sex-linked inheritance listed just before the case study. Which individuals in figure 5.2 demonstrate principle 1?

Bill, Terry, Greg, and Jenny.

2. Which individuals in figure 5.2 represent principle 2?

Carl, Terry, and Greg.

3. Which individuals in figure 5.2 represent principle

Florence, Jessica, Terry, and Greg.

4. Why are none of the males in figure 5.2 shown as carriers of hemophilia?

Males cannot carry hemophilia because it is an X-linked disease and males only have a single X chromosome. If the male has an X, he has the disease.

5. What is the probability that Marcy and Tom will have any child with hemophilia (irrespective of sex)? Show how you calculate this.

The probability of Marcy and Tom having a child with hemophilia is 12.5%. This is because Marcy has a 50% chance of being a carrier. Marcy’s children in turn have a 50% chance of receiving a copy of the X chromosome. Thus, there is a 25% chance that any of the children would receive a copy of the recessive X allele from Marcy. Tom does not have hemophilia, so we know that the gene on his X chromosome is normal. Therefore, only Marcy and Tom’s sons could have hemophilia. The total probability of Marcy and Tom having a child with hemophilia is 12.5% which brakes down mathematically (0.5)(0.5)(0.5) = .125.

6. Suppose Marcy becomes pregnant and has an amniocentesis, a prenatal cell-sampling technique that can identify the sex of a child (among other things). She finds that she is going to have a baby girl. Should she be worried that the baby will have hemophilia? Why or why not? Suppose she decides to be sterilized after her baby’s birth, so she will have only this one child. Should she be concerned that her grandchildren will have hemophilia? Why or why not?

Marcy should not be worried that the baby girl will have hemophilia.…...

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